Periodontal Diseases: Bug Induced, Host Promoted
نویسندگان
چکیده
1 Department of Oncology and Diagnostic Sciences, Dental School, University of Maryland, Baltimore, Maryland, United States of America, 2 Graduate Program in Life Sciences, Molecular Microbiology and Immunology Program, University of Maryland, Baltimore, Maryland, United States of America, 3 Department of Microbiology and Immunology, School of Medicine, University of Maryland, Baltimore, Maryland, United States of America
منابع مشابه
Host Modulatory Therapy: A Novel Approach in Periodontal Therapy
Although bacterial plaque is primary etiologic factor in the initiation and progression of periodontal diseases, the host’s reactions to the presence of the bacteria are the one which mediates the periodontal tissue destruction. The periodontal tissue destruction is believed to be due to the host response, it is logical to consider therapeutic approaches that modulate the host response in addit...
متن کاملA Study of Periodontal Disease in Children and Adolescents with Type 1 Diabetes
Marginal periodontium is the seat of acute and chronic diseases that pose a particular problem in general pathology of these diseases uman. The susceptibility to this disease is variable, depending on the host response to periodontal pathogens. Although bacteria causes an induced inflammatory periodontal disease plaque, clinical disease progression is influenced by genetic acquire factors that ...
متن کاملAnimal Models for Periodontal Disease
Animal models and cell cultures have contributed new knowledge in biological sciences, including periodontology. Although cultured cells can be used to study physiological processes that occur during the pathogenesis of periodontitis, the complex host response fundamentally responsible for this disease cannot be reproduced in vitro. Among the animal kingdom, rodents, rabbits, pigs, dogs, and no...
متن کاملEpigenetic Modifications of Host Genes Induced by Bacterial Infection
Introduction: Epigenetic mechanisms regulate expression of the genome to generate various cell types during development or coordinate cellular responses to external stimulus. While epigenetics is of fundamental importance in eukaryotes, it plays a different role in bacteria. This article uncovers the most important recent data on how bacteria can alter epigenetic marks and can also contribute t...
متن کاملRole of Periodontal Infection in Cardiovascular Disease: a Current Perspective
Oral pathogens play a causal role in Cardiovascular Disease (CVD) that is largely driven by inflammation and host immune response. Clinico-epidemiological and animal studies provide a strong link between periodontal disease (PD) and CVD, both of which are highly prevalent, complex disease processes with common risk factors. Genes involved in inflammation, matrix degeneration and immune response...
متن کامل